Diagnostic Criteria for PPF:
To diagnose PPF, all three of the following must be present:
Underlying fibrosing ILD (non-IPF), with imaging or histology showing fibrosis.
Evidence of progression within the past year, based on at least one of the following:
1.Worsening respiratory symptoms, such as increasing dyspnea or cough.
2.Decline in lung function, especially:
Absolute decline in FVC ≥ 5% predicted
Decline in DLCO (diffusing capacity for carbon monoxide) ≥ 10% predicted
3.Progressive fibrosis on imaging, shown by:
Increased reticulation
New ground-glass opacities with traction bronchiectasis
Increased honeycombing
No alternative explanation (e.g., infection, heart failure, pulmonary embolism).
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.Dr.Ilangho