ILD with family history - differential diagnosis

 Differential diagnosis of ILD with family history:

1. Idiopathic pulmonary fibrosis - most common form of familial ILD presenting as UIP pattern
2. Other idiopathic interstitial pneumonia - NSIP, cryptogenic organizing pneumonia
3. Connective tissue disorder associated ILD - rheumatoid arthritis, scleroderma associated ILD
4. Hypersensitivity pneumonitis - due to shared environmental exposure
5. Genetic mutations - Surfactant protein mutations (SFTPA2, SFTPC, ABCA3), telomeropathies (TERT, TERC), Hermansky pudlak syndrome, MUC5B polymorphism
6. Sarcoidosis