Distribution: Random (hematogenous) distribution with no centrilobular clustering or polygonal secondary-lobule pattern; nodules are bilateral and diffuse across all lung zones (may show mild basilar predominance acutely and mild upper-zone predominance chronically).
Margins and background: Nodules often sharply marginated but can be ill-defined; ground-glass attenuation or interlobular septal thickening/reticular change may be present superimposed on the nodules.

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Hi
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.Dr.Ilangho