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.ATS GUIDELINES OF TB DEFAULT AND RELAPSE (1) 1.WHY FASCIAL PUFFINESS OCCURS FIRST IN RENAL EDEMA (1) Acute (2) ACUTE EXACERBATION OF COPD CRITERIA (2) ACUTE EXACERBATION OF ILD CRITERIA (1) ACUTE EXACERBATION OF IPF criteria (1) AE COPD (1) Air crescent sign and Monod sign (1) Alveolar arterial oxygen gradient (1) Aminophylline in asthma (1) Amphoric breathing (1) Anuria and oliguria definition (1) apical cap (1) Apical impulse (1) Assessment of respiratory muscle strength (1) Asthma PEF variablity (1) Att in hepatotoxicity (1) ATT weight band recent (1) Austin flint murmur and Graham steel murmur (1) BEQ (1) BMI (1) Borg dyspnoea score (1) Breathlessness - Aggravating relieving factors (1) breathlessness-sherwood jones (1) Bronchiectasis- Definition (1) BRONCHOPULMONARY SEGMENTS (1) Cardinal symptoms: aggravating and relieving facto (1) Cardinal symptoms: aggravating and relieving factors (1) Causes of chest pain aggrevated by cough (1) Causes of localised bulging of chest wall (1) Causes of orthopnea (1) Causes of palpitation (1) Causes of Unilateral pedal edema (1) Cavity (1) check post (1) Chest physiotherapy (1) Chromogranin A (1) Chronic (2) Classification (1) Clubbing (1) clubbing -mechanism of (1) Clubbing Unilateral (1) CLUBBING-PATHOGENESIS PDGF (1) cobb's angle-In Kyphoscoliosis Cobb's angle above which can be operated (1) Cobbs angle (1) Complications of Tuberculosis (1) Cor pulmonale (1) Cough reflex (2) Cough- aggravating factors (1) Cultures- significant colony count (1) Cyst/Bulla/Bleb (1) Cystic Fibrosis- Female infertility (1) DD of Orthopnoea (1) definition (1) DNB question bank (1) Drugs causing breathlessness (1) dysphagia - approach (1) Dyspnea - Causes of acute dyspnea (1) ECG FEATURES OF DEXTROCARDIA (1) Emphysema (1) Emphysema and chronic bronchitis definition (1) Empyema necessitans (1) Exacerbation of ILD (1) Factitious asthma (1) Familial ILD differential diagnosis (1) Fever of unknown origin (1) fibrinolytics in plef (1) FORMOTEROL (1) Gastro Intestinal Tract and abdominal symptoms (1) Gram negative cocci & gram positive bacilli (1) HAM (1) Hemothorax (1) Honeycombing in HRCT (1) Hydropneumothorax- sound of Coin test (1) Hyperventilation syndrome (1) IDSA sinusitis management (1) ILD CLASSIFICATION (1) ILO classification for pneumoconiotic opacities (1) Impalpable apical impulse (2) INDICATIONS FOR NIV IN COPD (1) Indications for steroids in Sarcoidosis (2) Krogg constant (1) Lung areas sensitive to pain (1) lung cancer- age group (1) Lung cancers-ALK inhibitors (1) MARKERS OF ILD (1) Massive hemoptysis (1) Massive hemoptysis criteria (1) Mines in Tamil Nadu (1) Muscles of respiration (2) Name reason for Potts spine (1) Nephrotic syndrome (1) NORMAL BREATH SOUNDS - mechanism (1) NORMAL THYMUS IN CT (1) NYHA (1) Orthopnea (1) Orthostatic hypotension (1) Pain- CRPS (1) Paracetamol -MOA (1) Parapneumonic effusion - classification (1) Pathophysiology of breath sounds (1) Pedal edema Aggravating and relieving factors (1) Penetration and exposure in Chest Xray (1) Perception of Dyspnoea (1) Pleuroscopy guidelines (1) PND causes (1) Pneumatocele (1) pneumonia phases of (1) Positional variation in chest pain (1) PPF criteria (1) Puddle sign (1) Pulmonary embolism (1) Pulsations in different areas- causes (1) Pulsus paradoxus (1) Pulsus paradoxus - Measuremen (2) RADS-Definition and Criteria (1) Respiratory system clinical examination (1) Rheumatoid arthritis - diagnostic criteria (1) S3 (1) S4 HEART SOUNDS (1) Serum cortisol (1) Sherwood jones classification (1) Shivering (1) Silhouette sign (1) Six minute walk test (1) Skodaic resonance (1) SLE Criteria (1) Sleep study and polysomnography (1) Spinoscapular distance (1) Split pleura sign (1) Subacute (2) Subpulmonic effusion (1) Surface anatomy -right minor fissure (1) Swellin (1) SYSTEMIC SCLEROSIS - Diagnostic criteria (1) Terminal respiratory unit (1) Test (1) Tidal percussion (1) Tongue in HIV (1) Upper respiratory tract (1) Velcro crackles (1) Vesicular breath sounds - Physiology (1) weight loss (1)

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Wednesday, May 28, 2025

Zoonotic pneumonias

 Chlamydia psittaci- Psittacosis- Inhalation of bird feces or respiratory secretions

Francisella tularensis- Tularemia- Contact with wild and pet animals, birds or arthropods ( ticks, deer, fly)

Pasteurella multocida - Pasteurellosis-  Feline and dog contact; chronic lung disease

Rhodococcus equi-  Rhodococcus pneumonia- Airborne droplets; contact with soil contaminated with horse, cow, or swine excrement

Yersinia pestis- Plague-  Contact with rodents, fleas; contact with plague pneumonia case

Bacillus anthracis Inhalation anthrax or woolsorter’s disease- Industrial; use of or contact with animal products in hobbies. 

Toxoplasmosis- Toxoplasma gondii- Contact with feline species

Hantavirus infectionx- Infected rodents mainly inhaling airborne virus particles from urine, droppings or saliva. 

Wednesday, May 21, 2025

CARDINAL SYMPTOMS OF CVS:

 1) Chest pain

2) Brreathlessness

3) Palpitation 

4) Syncope

5) Edema

6) Fatigue

CAUSES OF PLEURITIC CHEST PAIN

CAUSES OF PLEURITIC CHEST PAIN

Pleuritic chest pain is a sharp, stabbing in the chest that worsens with respiratory movements such as deep breathing, coughing, sneezing, or laughing.

CAUSES:

1. Infectious Causes: These are among the most common reasons for pleuritic chest pain.

Viral Infections 

Bacterial Infections: Pneumonia, Tuberculosis

Fungal Infections: Though less common, fungal infections can also inflame the pleura, especially in individuals with weakened immune systems.

Parasitic Infections


2. Inflammatory and Autoimmune Conditions:

Pleuritis due to inflammation caused by conditions such as SLE, Rheumatoid arthritis, Sarcoidosis

Pleural Effusion

3. Cardiovascular Causes:

Pulmonary Embolism

Pericarditis


4. Neoplastic Causes (Cancers):

Lung Cancer invading or irritating the pleura.

I Mesothelioma

Pleural Metastatic Cancers


5. Traumatic Causes:

Rib Fractures or Chest Injury

Thoracic surgery or other procedures involving the chest can lead to temporary pleuritic pain.

ILD with family history - differential diagnosis

 Differential diagnosis of ILD with family history:

  1. Idiopathic pulmonary fibrosis - most common form of familial ILD presenting as UIP pattern
  2. Other idiopathic interstitial pneumonia - NSIP, cryptogenic organizing pneumonia
  3. Connective tissue disorder associated ILD - rheumatoid arthritis, scleroderma associated ILD
  4. Hypersensitivity pneumonitis - due to shared environmental exposure
  5. Genetic mutations - Surfactant protein mutations (SFTPA2, SFTPC, ABCA3), telomeropathies (TERT, TERC), Hermansky pudlak syndrome, MUC5B polymorphism
  6. Sarcoidosis

Wednesday, May 14, 2025

Health effects of dyes and chemicals used in Printing press

Process: Adhesive laminating 

Risk: Isocyanate prepolymers can cause an irritation of the airways and lungs leading to occupational asthma.


Process: Digital (ink-jet) printing

 Risk: Carbon present in black ink can cause lung irritation. Methyl ethyl ketone and propanol can cause abnormal heart rhythm and rate and can affect the liver and kidneys on long term exposure.


Process: UV lamps for photo processing, UV curing and high speed printing – ink misting 

Risk: Acrylates and methcrylates in  fumes can cause irritation of respiratory tracts with the potential for occupational asthma as well as severe headaches and nausea.


Health Effects Of Chemicals Used In Printing

Process: Etching, Engraving, Platemaking, Photographic Reproduction 

Risk: Nitric, sulphuric and hydrofluoric acids can cause skin burns, eye damage and blisters.


Process: Concentrated photographic developer or fixer solutions 

Risk: Acidic salt solutions and Hydroquinone can irritate eyes and even cause dermatitis


Process: UV and infra red curable inks, varnishes and lacquers 

Risk: Reactive acrylates or methacrylate’s can cause corrosion of the skin, eyes and mucous membranes.


Process: Lithographic platemaking, Gravure cylinder preparation and photoengraving. 

Risk: Ammonium, potassium and sodium dichromate’s are all very corrosive and can cause deep ulcers as well as a risk of cancer.


Process: Lithographic fount solution, blanket restorers, cleaning solvents, Gravure and flexographic Risk: Alcohol, Esters and Ketones can cause dermatitis, dizziness and other effects of the central nervous system.


Process: Flexographic, Dyeline Printing and Screen Inks Risk: Perchloroethylene, Ammonium hydroxide and Ketones can cause dizziness, drowsiness and other effects on the central nervous system via inhalation.


Process: Screen Cleaning chemicals 

Risk: Strong alkalis such as concentrated sodium or potassium hydroxide, Oxidisers and sodium hypochlorite solvents can cause corrosion of the skin, eyes and mucous membrane as well as dizziness and drowsiness

Progressive Pulmonary Fibrosis

 

Diagnostic Criteria for PPF:

To diagnose PPF, all three of the following must be present:


Underlying fibrosing ILD (non-IPF), with imaging or histology showing fibrosis.


Evidence of progression within the past year, based on at least one of the following:


1.Worsening respiratory symptoms, such as increasing dyspnea or cough.


2.Decline in lung function, especially:


Absolute decline in FVC ≥ 5% predicted


Decline in DLCO (diffusing capacity for carbon monoxide) ≥ 10% predicted


3.Progressive fibrosis on imaging, shown by:

Increased reticulation

New ground-glass opacities with traction bronchiectasis

Increased honeycombing


No alternative explanation (e.g., infection, heart failure, pulmonary embolism).

Wednesday, May 7, 2025

Aggravating factors for chief complaints

 AGGRAVATING FACTORS OF CARDINAL SYMPTOMS- MNEMONICS


COUGH:


PDFCE 


Pollution, Pollen, Posture

Drugs, Diurnal, Dry air

Food

Cold weather, Common cold

Exercise



SPUTUM


 "DRIVE DUST"

 

D – Dust exposure

R – Respiratory infections

I – Irritants (e.g., smoke, fumes)

V – Viral infections

E – Exercise or exertion

D – Dry air

U – Upper respiratory tract conditions (e.g., postnasal drip)

S – Smoking

T – Temperature changes (cold air or sudden temperature drops)


Breathlessness: 


 "BREATHE HARD"

 

B – Body position (e.g., lying flat in orthopnea)

R – Respiratory infections

E – Exercise or exertion

A – Anxiety or emotional stress

T – Temperature extremes (cold or heat)

H – Hypoxia or high altitude

E – Environmental triggers (allergens, pollutants)

H – Heart failure or fluid overload

A – Anemia

R – Reflux (gastroesophageal reflux disease)

D – Drugs (e.g., beta-blockers, 


WHEEZE:


“BREATHE WHEEZE”


B – Bronchial irritants (smoke, pollution)

R – Respiratory infections (viral or bacterial)

E – Exercise

A – Allergens (pollen, dust mites, animal dander)

T – Temperature changes (cold air)

H – Hormonal changes (pregnancy, menstruation)

E – Emotions (stress, anxiety)

W – Workplace irritants (occupational exposures)

H – Household triggers (perfumes, cleaning agents)

E – Environmental changes (high altitude)

E – Exposure to drugs (NSAIDs, beta-blockers)

Z – Zzz… sleep (nocturnal asthma triggers)

E – Eating (GERD-induced wheeze)



CHEST PAIN:


“CHEST PAINS”


C – Coughing or deep breathing (pleuritic pain)

H – Heat or cold exposure (vasospastic angina)

E – Emotion or stress (psychogenic pain, angina)

S – Swallowing (esophageal causes like GERD or spasm)

T – Trauma or movement (musculoskeletal pain, costochondritis)

P – Physical exertion (angina, cardiac ischemia)

A – Alcohol or large meals (GERD or esophageal spasm)

I – Infections (pleuritis, pericarditis, pneumonia)

N – Nighttime (GERD-related pain due to supine position)

S – Specific postures (pericarditis, GERD, musculoskeletal pain)


HEMOPTYSIS:


“COUGH BLOOD”


C – Coughing (increases airway pressure, ruptures small vessels)

O – Overexertion (exacerbates vascular stress)

U – Upper respiratory tract infections

G – GERD or vomiting (irritation of airways)

H – High altitude (pulmonary hypertension)

B – Bronchial infections (bronchitis, bronchiectasis)

L – Lung malignancy (coughing or irritation)

O – Operations (post-procedural bleeding, e.g., bronchoscopy)

O – Oral anticoagulants (worsen bleeding)

D – Deep breaths or physical strain (ruptures fragile capillaries)

Pathophysiology of early inspiratory crackles in OAD

Premature Airway Opening in Early Inspiration:
During the early phase of inspiration, as negative intrathoracic pressure builds, these collapsed small airways pop open. This sudden opening generates transient sounds—early inspiratory crackles.

Correlation with Disease Severity:
The presence of early inspiratory crackles often correlates with moderate to severe airway obstruction, especially in patients with chronic bronchitis or emphysema.